Floré Clinical Review: Custom Probiotics
Floré (by Sun Genomics) operates on a unique model: perform high-level whole genome sequencing, and then physically compound a bespoke probiotic specifically tailored to the deficiencies found in your sample.
Methodology & Technology
Floré uses Whole Genome Sequencing (WGS), which is highly accurate down to the strain level. This is superior to basic 16S testing and competitive with the shotgun metagenomics used by Thorne and ZOE.
Their lab processes look specifically for the presence of over 23,000 microbes, identifying not just beneficial bacteria, but opportunistic pathogens and fungi.
The Custom Probiotic Solution
As discussed in our Probiotics vs Prebiotics guide, buying generic, off-the-shelf probiotics is clinically inefficient. Floré's primary value proposition is their custom formulation.
If your results show high levels of histamine-producing bacteria, they will explicitly exclude histamine-producing probiotic strains (like L. casei) from your custom formula and include histamine-degrading strains (like B. infantis). They will also incorporate specific prebiotics and botanical extracts based on your inflammation markers.
The SIBO Risk Factor
If you are suffering from undiagnosed SIBO, adding any probiotics (even custom ones) or prebiotics can rapidly exacerbate your symptoms. Floré cannot diagnose SIBO. Ensure you have ruled out SIBO via breath testing before starting a heavy probiotic protocol.
Final Verdict
For individuals actively struggling with dysbiosis (post-antibiotic use, chronic diarrhea) who are tired of trial-and-error with generic supplements, Floré is highly effective. The ongoing cost is significant ($79/month for the custom pills), but it replaces the need for purchasing multiple disparate supplements.